{"id":10,"date":"2024-12-26T19:50:13","date_gmt":"2024-12-26T19:50:13","guid":{"rendered":"https:\/\/feno.ro\/?page_id=10"},"modified":"2024-12-27T20:31:24","modified_gmt":"2024-12-27T20:31:24","slug":"ce-este-feno","status":"publish","type":"page","link":"https:\/\/feno.ro\/index.php\/ce-este-feno\/","title":{"rendered":"Ce este FeNO?"},"content":{"rendered":"\t\t
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Ce este FeNO?<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Testarea FeNO in astm<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Potrivit Asthma UK, aproximativ 5,4 milioane de persoane din Marea Britanie primesc tratament pentru astm8, iar aproximativ 300 de milioane de persoane din \u00eentreaga lume sunt considerate a fi afectate de astm9. Se \u00een\u021belege c\u0103, \u00een medie, 3 persoane mor zilnic din cauza atacurilor de astm \u00een Marea Britanie8. Se crede c\u0103 NHS cheltuie\u0219te aproximativ 1 miliard de lire sterline pe an pentru tratarea \u0219i gestionarea simptomelor astmului8. Astmul este denumit \u00een mod obi\u0219nuit o boal\u0103 inflamatorie care afecteaz\u0103 c\u0103ile respiratorii ale unei persoane, duc\u00e2nd la hiper-reactivitate, obstruc\u021bie, hiperproduc\u021bie de mucus \u0219i remodelare a peretelui c\u0103ilor respiratorii9. De\u0219i inflama\u021bia eozinofil\u0103 a c\u0103ilor respiratorii este o caracteristic\u0103 cheie a astmului bron\u0219ic, foarte pu\u021bine metode sunt disponibile pentru m\u0103surarea inflama\u021biei eozinofile a c\u0103ilor respiratorii. Inflama\u021bia eozinofil\u0103 a c\u0103ilor respiratorii poate fi m\u0103surat\u0103 prin m\u0103surarea eozinofilelor \u0219i a proteinei cationice eozinofile (ECP) \u00een sput\u0103 sau ECP-urile pot fi m\u0103surate \u00eentr-o prob\u0103 de s\u00e2nge10. Aceste metode sunt de obicei considerate standard de aur, dar sunt foarte consumatoare de timp, costisitoare \u0219i nu sunt disponibile \u00een mod obi\u0219nuit.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Majoritatea inflama\u021biei c\u0103ilor respiratorii ale pacien\u021bilor cu astm bron\u0219ic este r\u0103spunsul Th2 condus de alergen11. Exist\u0103 dovezi semnificative din literatura extern\u0103 care sugereaz\u0103 c\u0103 FeNO (oxid nitric) este un instrument cheie de biomarker pentru inflama\u021bia tractului respirator11. Se crede c\u0103 nivelurile crescute de FeNO \u00een astm provin din NOS2 inductibil exprimat \u00een c\u0103ile respiratorii inflamate11. NObreath\u00ae ofer\u0103 un ajutor alternativ pentru diagnosticarea astmului bron\u0219ic, care este non-invaziv \u0219i semnificativ mai rentabil dec\u00e2t metodele standard de aur actuale pentru diagnosticarea inflama\u021biei eozinofile a c\u0103ilor respiratorii, mai departe \u00een diagnosticul astmului. Ca urmare a cantit\u0103\u021bilor substan\u021biale de literatur\u0103 care sus\u021bine m\u0103sur\u0103torile FeNO ca un biomarker eficient pentru astm \u0219i alte inflama\u021bii ale c\u0103ilor respiratorii, testarea respira\u021biei FeNO este acum recomandat\u0103 \u00een ghidurile NICE ca ajutor pentru diagnosticarea astmului alergic12. Literatura de specialitate sugereaz\u0103, de asemenea, capacitatea de m\u0103surare a FeNO de a fi folosit\u0103 ca instrument de management bun pentru astm bron\u0219ic13, evalu\u00e2nd eficacitatea tratamentelor pentru pacien\u021bi, optimiz\u00e2nd tratamentele pentru astm.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Beneficiile FeNO<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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  • Non-invaziv, rapid \u0219i u\u0219or de efectuat5<\/li>
  • Afi\u0219eaz\u0103 r\u0103spunsul pacientului la tratament, permi\u021b\u00e2nd prescrierea corect\u0103 a medicamentelor \u0219i ajust\u0103ri mai sigure\/monitorizate<\/li>
  • Ajut\u0103 la identificarea pacien\u021bilor care necesit\u0103\/nu necesit\u0103 tratament continuu6<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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    • Arat\u0103 conformitatea pacientului<\/li>
    • S-a dovedit a fi superioar\u0103 majorit\u0103\u021bii testelor conven\u021bionale ale func\u021biei pulmonare, cum ar fi \u00eenregistrarea debitului maxim \u0219i spirometria5<\/li>
    • Ajut\u0103 la diferen\u021bierea \u00eentre astmul alergic (eozinofil) \u0219i non-alergic7.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

      Ce este FeNO? Testarea FeNO in astm Potrivit Asthma UK, aproximativ 5,4 milioane de persoane din Marea Britanie primesc tratament pentru astm8, iar aproximativ 300 de milioane de persoane din \u00eentreaga lume sunt considerate a fi afectate de astm9. Se \u00een\u021belege c\u0103, \u00een medie, 3 persoane mor zilnic din cauza atacurilor de astm \u00een Marea […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-10","page","type-page","status-publish","hentry"],"rankMath":{"parentDomain":"feno.ro","noFollowDomains":[],"noFollowExcludeDomains":[],"noFollowExternalLinks":false,"featuredImageNotice":"The featured image should be at least 200 by 200 pixels to be picked up by Facebook and other social media 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